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REFLECTIONS
                                                                                                                Hypertension
     Hypertension Global Newsletter #7 2024





                  TABLE OF CONTENTS

            KEY ARTICLES                                        Welcome back to the REFLECTIONS Hypertension
                                                                Global Newsletter series, which draws on the expertise of
          GUIDELINES                                                                                            Hypertension
                                                                international physicians to summarise the latest clinical and
          2024 ESC guidelines for the management of             real-world evidence in the field of hypertension and reflect
          elevated blood pressure and hypertension.             on the clinical impact of these new data on the management
          McEvoy JW, et al. Eur Heart J. 2024 Aug
          30:ehae178. doi: 10.1093/eurheartj/ehae178.           of patients with hypertension.
          Online ahead of print.
                                                                Since our last newsletter, there have been very many new
          The management of elevated blood pressure             and interesting publications in the active field of clinical
          in the acute care setting: A scientific statement     research in hypertension, therefore the Scientific Planning
          from the American Heart Association. Bress AP,
          et al. Hypertension. 2024 Aug;81(8):e94-e106.         Committee was tasked with choosing from an extensive
                                                                list of articles from high-quality scientific journals. To make
          TARGETS AND TREATMENT                                 this last selection, we privileged novel findings rather
          Optimal antihypertensive systolic blood pressure:     than confirmation papers, and articles directly applying to
          A systematic review and meta-analysis. Whelton        antihypertensive treatment in routine clinical practice. This
          PK, et al. Hypertension. 2024 Sep 12. doi: 10.1161/   newsletter will focus on 1) recent clinical guidelines from the
          HYPERTENSIONAHA.124.23597. Online ahead of
          print.                                                ESC and the AHA, 2) targets and treatments, and 3) special
                                                                populations – obesity. As with previous newsletters, we
          Lowering systolic blood pressure to less than         invite you to interact with this through links to commentary
          120 mm Hg versus less than 140 mm Hg in
          patients with high cardiovascular risk with and       videos from authors of the publications, short video clinical
          without diabetes or previous stroke: an open-         perspectives from our SPC, and delve into the articles
          label, blinded-outcome, randomised trial. Liu J,      through hyperlinks for in-depth study.
          et al. ESPRIT Collaborative Group. Lancet. 2024 Jul
          20;404(10449):245-255.                                We are also pleased to share our Conference Corner,

          Therapeutic inertia with initial low-dose             where this time we highlight some abstracts of interest
          quadruple combination therapy for hypertension:       from the recent 2024 ESC Congress which took place in
          Results from the QUARTET trial. Wang N, et al.        London, England.
          Hypertension. 2024 May;81(5):1087-1094.
                                                                Prof. Laurent (Chair)
          Semaglutide and blood pressure: An individual
          patient data meta-analysis. Kennedy C, et al.
          Eur Heart J. 2024 Sep 1:ehae564. doi: 10.1093/        SCIENTIFIC PLANNING COMMITTEE
          eurheartj/ehae564. Online ahead of print.

          SPECIAL POPULATIONS                                          Prof. Stéphane Laurent      Prof. Diego Araiza
                                                                       (France)                    (Mexico)
          Medications for obesity: A review. Gudzune KA,
          Kushner RF. JAMA. 2024 Aug 20;332(7):571-584.

          ADDITIONAL ARTICLES OF INTEREST                              Prof. Adriana Camargo       Dr. Om Narayan
                                                                       (Brazil)                    (Australia)
          CONFERENCE CORNER

          HIGHLIGHTED ABSTRACTS OF INTEREST                            Prof. Nqoba Tsabedze        Dr. Michal Fikrle
          FROM THE ESC 2024 CONFERENCE                                 (South Africa)              (Czech Republic)
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